Also known as: Ethylene dichloride. CAS Number: 107-06-2. A
colorless, toxic liquid compound that is used chiefly as a
solvent. Chemical formula = C2H4Cl2. Molecular weight = 98.96 g/mol.
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Exposure to low levels of 1,2-Dichloroethane can occur from
breathing ambient or workplace air. Inhalation of concentrated
ethylene dichloride vapor can induce effects on the human nervous
system, liver, and kidneys, as well as respiratory distress,
cardiac arrhythmia, nausea, and vomiting. Chronic (long-term)
inhalation exposure to ethylene dichloride produced effects on
the liver and kidneys in animals. No information is available on
the reproductive or developmental effects of ethylene dichloride
in humans. Decreased fertility and increased embryo mortality
have been observed in inhalation studies of rats.
Epidemiological studies are not conclusive regarding the
carcinogenic effects of ethylene dichloride, due to concomitant
exposure to other chemicals. Following treatment by gavage
(experimentally placing the chemical in the stomach), several
tumor types were induced in rats and mice. EPA has classified
ethylene dichloride as a Group B2, probable human carcinogen.