CAS Number: 106-46-7. One of the group of organic halogen
compounds replacing the two hydrogen atoms in benzene by
chlorine atoms. This isomer is a white solid with a
characteristic penetrating odor. It is used mainly as an
insecticidal fumigant against moths, as a space deodorizer, as
a general insecticide and fungicide on crops, and as a chemical
intermediate for plastics, dyes, pharmaceuticals and other
organic compounds. Chemical formula = C6H4Cl2. Molecular weight
= 147.02 g/mol.
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The primary exposure to 1,4-dichlorobenzene is from breathing
contaminated indoor air. Acute (short-term) exposure to
1,4-dichlorobenzene, via inhalation in humans, results in
irritation of the skin, throat, and eyes. Chronic (long-term)
1,4-dichlorobenzene inhalation exposure in humans results in
effects on the liver, skin, and central nervous system (CNS). No
information is available on the reproductive, developmental, or
carcinogenic effects of 1,4-dichlorobenzene in humans. A
National Toxicology Program (NTP) study reported that
1,4-dichlorobenzene caused kidney tumors in male rats and liver
tumors in both sexes of mice by gavage (experimentally placing
the chemical in their stomachs). EPA has classified
1,4-dichlorobenzene as a Group C, possible human carcinogen.