CAS Number: 106-50-3. An off-white crystal or powder. Most
commonly used in hair dyes, and as a dye intermediate. It is
also used as a photographic developing agent and a chemical
intermediate and as a vulcanization accelerator and as an
antioxidant in rubber compounds. Prlonged skin contact is not
recommended because the compound is known to cause skin
irriations in humans. Chemical Formula = C6H8N. Molecular weight
= 108.4 g/mol.
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p-Phenylenediamine is primarily used as a dye intermediate and as
a dye. Acute (short-term) exposure to high levels of
p-phenylenediamine may cause severe dermatitis, eye irritation
and tearing, asthma, gastritis, renal failure, vertigo, tremors,
convulsions, and coma in humans. Eczematoid contact dermatitis
may result from chronic (long-term) exposure in humans. In rats
and mice chronically exposed to p-phenylenediamine in their diet,
depressed body weights, but no other clinical signs of toxicity,
were observed in several studies. No information is available on
the reproductive, developmental, or carcinogenic effects of
p-phenylenediamine in humans. EPA has not classified
p-phenylenediamine with respect to carcinogenicity.