2,4-Toluene diisocyanate

CAS Number: 584-84-9. A colorless, yellow or dark liquid with a
sharp, pungent odor. It is used as a chemical intermediate in the
production of polyurenthane products. Chemical formula =
C9H6N2O2. Molecular weight = 174.15 g/mol.

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2,4-Toluene diisocyanate is primarily used as a chemical
intermediate in the production of polyurenthane products.
2,4-Toluene diisocyanate is extremely toxic from acute
(short-term) and chronic (long-term) exposures. Acute exposure
to high levels of 2,4-toluene diisocyanate in humans, via
inhalation, results in severe irritation of the skin and eyes and
affects the respiratory, gastrointestinal, and central nervous
systems (CNS). Chronic inhalation exposure to 2,4-toluene
diisocyanate in humans has resulted in significant decreases in
lung function in workers, an asthma-like reaction characterized
by wheezing, dyspnea, and bronchial constriction. Animal studies
have reported significantly increased incidences of tumors of the
pancreas, liver, and mammary glands from exposure to 2,4-toluene
diisocyanate via gavage (experimentally placing the chemical in
the stomach). The International Agency for Research on Cancer
(IARC) has classified 2,4-toluene diisocyanate as a Group 2B,
possible human carcinogen.