Methyl tert-Butyl Ether

Methyl tert-butyl ether is used as a gasoline additive. Exposure
may occur by breathing air contaminated with auto exhaust or
gasoline fumes while refueling autos. Respiratory irritation,
dizziness, and disorientation have been reported by some
motorists and occupationally exposed workers. Acute (short-term)
exposure of humans to methyl tert-butyl ether also has occurred
during its use as a medical treatment to dissolve cholesterol
gallstones. Chronic (long-term) inhalation exposure to methyl
tert-butyl ether has resulted in central nervous system (CNS)
effects, respiratory irritation, liver and kidney effects, and
decreased body weight gain in animals. Developmental effects
have been reported in rats and mice exposed via inhalation. EPA
has not classified methyl tert-butyl ether with respect to
potential carcinogenicity.