Also known as: Propylene Dichloride. CAS Number: 78-87-5. A clear
liquid with a sweet, chloroform-like odor. It is used as an
insecticidal fumigant, a pesticide, a dry cleaning agent, and a
solvent in the plastics, resins and metals industries. Chemical
formula = C3H6Cl2. Molecular weight = 112.99 g/mol.
1,2-Dichloropropane is used as a chemical intermediate in several
industries. Acute (short-term) inhalation exposure to high levels
of propylene dichloride by humans results in effects on the
lungs, gastrointestinal system, blood, liver, kidneys, central
nervous system, and eyes. Limited information is available on
the chronic (long-term), reproductive, developmental, and
carcinogenic effects of propylene dichloride in humans. Animal
studies have reported effects on the respiratory system and blood
from chronic inhalation exposure. Animal studies have reported
developmental effects from propylene dichloride exposure by
gavage (experimentally placing the chemical in the stomach).
Animal studies have reported an increased incidence of mammary
gland tumors in female rats and liver tumors in male and female
mice given propylene dichloride by gavage. EPA has provisionally
classified propylene dichloride as a Group B2, probable human
carcinogen.