CAS Number: 101-77-9. Pale yellow crystals that darken when
exposed to air, and have an amine-like odor. Used primarily to
produce 4,4-'methylenedianiline diisocyanate and other polymeric
isocyanates, which are used to manufacture polyurethane foams.
Also used as a curing agent for epoxy resins and urethane
elastomers, as a corrosion preventative for iron, as an
antioxidant for lubricating oils, as a rubber processing
chemical, amd as an intermediate in the manufacture of
elastomeric fibers (e.g., Spandex). Chemical formula = C13H14N2.
Molecular weight = 198.26 g/mol.
4,4'-Methylenedianiline (MDA) is primarily used to produce
4,4'-methylenedianline diisocyanate and other polymeric
isocyanates. Acute (short-term) oral and dermal exposure to MDA
causes liver damage in humans and animals. MDA can irritate the
skin and eyes in humans. No information is available on the
chronic (long-term), reproductive, developmental, or carcinogenic
effects of MDA in humans. In rats and mice exposed to the
dihydrochloride salt of MDA in their drinking water,
statistically significant increases in the incidence of several
types of tumors, including liver and thyroid tumors, were
reported. EPA has not classified MDA for carcinogenicity. The
International Agency for Research on Cancer (IARC) has classified
MDA as a Group 2B, possible human carcinogen.