4,4'-Methylenediphenyl Diisocyanate

CAS Number: 101-68-8. White to light-yellow, odorless flakes.
Used to produce polyurethane foams. Chemical formula =
C15H10N2O2. Molecular weight = 250.3 g/mol.

Glossary Term Acronym
MDI
Glossary Term Category
Glossary Term Show In Main
Yes
Glossary Term Ext Def

The commercial form of 4,4'-methylenediphenyl diisocyanate (MDI)
is used to produce polyurethane foams. Acute (short-term)
inhalation of high concentrations of MDI may cause sensitization
and asthma in humans. Acute dermal contact with MDI has induced
dermatitis and eczema in workers. MDI has been observed to
irritate the skin and eyes of rabbits. Chronic (long-term)
inhalation exposure to MDI has been shown to cause asthma,
dyspnea, and other respiratory impairments in workers.
Respiratory effects have also been observed in animals. No
adequate information is available on the reproductive,
developmental, or carcinogenic effects of MDI in humans. EPA has
classified MDI as a Group D, not classifiable as to human
carcinogenicity.